A motorcyclist remains in hospital with life-threatening injuries after a crash involving four vehicles on Sunday.
A van, a car and two motorbikes were involved in the collision which took place at the junction of the A470 with the A4215 between Libanus and RAC bends.
The rider of a Harley Davidson was taken to hospital with life-threatening injuries meanwhile the rider of a Suzuki motorbike suffered minor injuries.
The police closed the road until 5pm following the accident at 2pm while they investigated the scene.
A Dyfed-Powys Police spokeswoman today (Monday, March 25) said: "Police were called to the A470 between Libanus and Storey Arms at 2pm on Sunday, March 24 to a report of a collision involving four vehicles.
"A van, car and two motorbikes were involved in the collision, which occurred at an unclassified junction that leads to the A4215.
"The rider of a Suzuki suffered minor injuries, and the rider of a Harley Davidson suffered life-threatening injuries and remains in hospital.
"The road was closed until just before 5pm while police investigated the scene.
"Police are appealing for witnesses, in particular looking for a white van type vehicle that turned right into the unclassified at the time of the collision."
The accident came after another road through the Brecon Beacons was closed on Sunday morning when a motorcyclist was involved in a fatal RTA near Crai reservoir.
It is also the second accident at that section of the A470 in four days as there was also a collision between two cars on Wednesday.
A Dyfed-Powys Police tweet put out at about 4pm on Sunday said: "We are at scene of an RTC on the A470 betw Libanus and the RAC bends - on the junction of the shortcut that runs from the A470 to the A4215. Road is CLOSED and will be for approx 90 mins. Time of update 1600 hrs. Please avoid the area and use diversions."
Anyone with information about the crash should contact the Brecon Roads Policing Team on 101, quoting reference 169 of March 24.